BA and MA Thesis Topics

ETH4D lists BA and MA thesis topics across ETH Zurich that are related to global development. If you are interested, please get in touch with the listed supervisor directly.

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Unravelling the spatial and biomechanical dynamic of fracture healing in mice

Fracture healing is a complex process that involves inflammation, angiogenesis, and bone remodeling. The remodelling process helps maintain bone density, repair micro-damage that occurs due to everyday activities, and adapt bones to the specific needs of an individual's body. Mechanical loading is a crucial factor in the regulation of fracture healing. The forces and strains experienced by the bone during everyday activities influence the cellular responses, callus formation, bone deposition, remodelling, and, ultimately, the successful recovery of the fractured bone. The mechanisms underlying spatial cell reorganization during loading, which contributes to fracture healing, remain unclear. The project aims to investigate and explore the fracture healing process of mice using spatial transcriptome changes in response to mechanical loading. By shedding light on this aspect, the project aims to contribute to the broader understanding of fracture healing and potentially pave the way for more effective treatment strategies in the future.

Keywords

Spatial transcriptomics, Dimensionality reduction, Spatial expression pattern, Spatial interaction, Cell Segmentation and Visualization, Fracture healing, Bone

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IDEA League Student Grant (IDL) , Semester Project , Course Project , Internship , Bachelor Thesis , Master Thesis , ETH for Development (ETH4D) (ETHZ) , ETH Zurich (ETHZ)

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Published since: 2024-03-07 , Earliest start: 2024-03-07 , Latest end: 2024-08-01

Organization Müller Group / Laboratory for Bone Biomechanics

Hosts Singh Amit

Topics Medical and Health Sciences , Mathematical Sciences , Information, Computing and Communication Sciences , Engineering and Technology , Biology , Physics

Pasteurizer development for biogas-powered effluent treatment

Anaerobic digestion (AD) is considered one of the oldest and most sustainable biological treatment technologies for stabilizing and reducing organic waste, including food waste, sewage sludge, industrial waste, and farm waste. AD transforms organic matter into biogas (60–70 vol-% of methane), thereby reducing the volume of the waste whilst destroying some of the pathogens present in the waste feedstocks and limiting odor problems associated with waste materials (Appels et al., 2008; Gerardi, 2003). AD is a promising energy, waste management, and sanitation solution in low-resource, low-income settings (Forbis-Stokes et al., 2016; Owamah et al., 2014). However, it does not fully eliminate pathogens for safe environmental discharge. Three ETH master students (Hardeman, 2022; Jäggi, 2023; Luz, 2022) iteratively developed and optimized the biogas reactor and the solution for sludge pasteurization to homogeneously heat the effluent and render the liquid safe for discharge. However, the technology needs further improvements and adaptations to operate reliably in continuous mode in all environmental conditions.

Keywords

thermodynamics, mechanical design, manufacturing, measurements

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Master Thesis , ETH for Development (ETH4D) (ETHZ) , ETH Zurich (ETHZ)

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Published since: 2024-02-02 , Earliest start: 2024-02-01 , Latest end: 2024-11-30

Applications limited to ETH Zurich , Department of Mechanical and Process Engineering

Organization Global Health Engineering

Hosts Tkaczuk Jakub

Topics Engineering and Technology

Analysis and treatment of wastewater from plastic recycling in Blantyre, Malawi

Monitoring and treatment of plastic washing wastewater from recycling processes is often overlooked, though the high pH, chemical oxygen demand, suspended solids, and oil and grease concentrations can be problematic (Ozdemir and Yel 2023). Treatment of wastewater from plastic recycling is critical to both public and environmental health, since solid waste, sanitation, and water are inextricably linked (Narayan et al. 2021). This thesis project will contribute to a closed-loop plastic recycling pilot for HDPE bottles in Blantyre, Malawi.

Keywords

wastewater, plastic recycling, resource conservation, low-income setting

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Master Thesis , ETH for Development (ETH4D) (ETHZ) , ETH Zurich (ETHZ)

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Published since: 2024-01-12 , Earliest start: 2024-02-01 , Latest end: 2024-09-30

Applications limited to ETH Zurich

Organization Global Health Engineering

Hosts Tkaczuk Jakub

Topics Engineering and Technology

Optimizing Membrane Technology for Water Filtration in Low and Middle-Income Settings

Openversum is dedicated to pioneering sustainable, cost-effective water filtration solutions for communities in low and middle-income regions. Our advancements in membrane technology represent a significant leap forward. However, continuous innovation is essential to optimize these membranes for local environmental conditions and budgetary constraints. Striking a balance between affordability, efficiency, and local adaptability is crucial for the widespread adoption of this technology.

Keywords

Membrane Science, Water Filtration, Low-Cost Production, Material Science, Polymer Chemistry, Industrial Upscaling, Sustainable Technology, Environmental Engineering, Water Purification

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Master Thesis , ETH for Development (ETH4D) (ETHZ)

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Published since: 2023-12-21 , Earliest start: 2024-01-07 , Latest end: 2024-09-30

Applications limited to Department of Mechanical and Process Engineering

Organization Global Health Engineering

Hosts Tkaczuk Jakub

Topics Engineering and Technology

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